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Multi electrode array approaches have been
2018-11-14
Multi-electrode array approaches have been proposed as a tool for detecting functional changes in electrically excitable cells, including neurons, exposed to drugs or toxins and allow use in high throughput studies (McConnell et al., 2012). Although there are a number of electrophysiological measure
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It remains elusive how ESCs recruit a larger number
2018-11-14
It remains elusive how ESCs recruit a larger number of DOs than tissue stem/progenitor ccr2 inhibitor during DNA licensing. It is possible that ESCs express a higher level of proteins that mediate DNA licensing. Alternatively, it could be due to their open and hyper-dynamic chromatin structure (Mat
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Descriptive analysis used medians with interquartile range I
2018-11-14
Descriptive analysis used medians with interquartile range (IQR) values. Statistical comparisons between the 3 NK groups ( Results Discussion Large cohorts for studying the correlation between NK cell deficiency and clinical events in humans are extremely rare. The study by Imai and colleagues
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3-Methyladenine A multi biomarker based outcome stratificati
2018-11-14
A multi-biomarker based outcome stratification model has also been advocated by Wong et al. that reliably estimated probability of mortality based on inflammatory markers along with conventional clinical and demographic data. Similar to our approach the sensitivity is much better than the specificit
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The investigated functional imaging technique has great pote
2018-11-14
The investigated functional imaging technique has great potentials. Diffusion-weighted MRI may provide an aid to establish the aggressiveness of prostate cancer and help predict those tumors most likely to progress rapidly. Prostate biopsies frequently underestimate the ‘true’ Gleason score of tumor
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The upper respiratory tract is the
2018-11-14
The upper respiratory tract is the natural niche for respiratory bacterial and viral pathogens and the origin for consecutive respiratory tract infections (RTI). Potential pathogenic bacteria are embedded in a cox 2 inhibitors of commensals, jointly forming the nasopharyngeal microbiota. Microbial c
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Multi gene host signatures are one
2018-11-14
Multi-gene host signatures are one such area of investigation. As reported in , Chandra and colleagues applied a computational method that allowed them to identify a transcript signature that can diagnose active TB (). In an “unbiased” approach to biomarker discovery, starting with RNA-Sequencing da
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br Duchenne muscular dystrophy DMD is an
2018-11-14
Duchenne muscular dystrophy (DMD) is an X-linked muscle disease affecting approximately 1 in 3600–6000 live male births () characterized by the lack of dystrophin, progressive skeletal muscle degeneration and cardiorespiratory failure. Although DMD is one of the best studied muscle disorders, no c
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The occurrence of an inflamed phenotype in
2018-11-14
The occurrence of an inflamed phenotype in CIMP-Atypical HNSCC raises the intriguing possibility that CIMP-Atypical HNSCC is caused by chronic inflammation: This corresponds to an emerging hypothesis that pathogen-related chronic inflammation causes some OSCCs, as periodontal disease is associated w
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Tumor relapse after radiotherapy is a significant challenge
2018-11-14
Tumor relapse after radiotherapy is a significant challenge to oncologists. Tumor recurrence was generally due to radiation resistance, which was determined by both the intrinsic characteristics and the extrinsic microenvironment of cancer C646 (Frank et al., 2010). The unique stem cell properties,
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br Stress Accelerates Telomere Shortening Although cellular
2018-11-14
Stress Accelerates Telomere Shortening Although cellular replication is a major contributor to telomere attrition, other factors can affect the rate at which telomeres shorten. For example, it has been extensively reported that telomere shortening is accelerated when calcifediol are exposed to m
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Similar rating EEMs with price and efficiency detail
2018-11-14
Similar rating EEMs with price and efficiency detail comparison with those of SMs (as per Table 1 in [1]), when processed with the cost effectiveness formulas and conditions given in [1], resulted encouraging values of annual energy savings, cost savings and payback periods. An example of such calcu
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All soilcrete specimens were cast in concrete
2018-11-14
All soilcrete specimens were cpi-613 in concrete cylinders (100mm in diameter, 200mm in high), vibrated for 20s on a vibration table and then covered to minimize water evaporation [1–3]. The molds were stripped after 24h, and the specimens were immersed in lime-saturated water at 20°C, until testin
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As stated previously the integration of cognitive flexibilit
2018-11-13
As stated previously, the integration of cognitive flexibility and emotion regulation is hypothesized to be bi-directional (Zelazo and Cunningham, 2007). Although it is clear that emotion regulation develops rapidly during the preschool years (Eisenberg, 2000), evidence of how specific emotion regul
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Forskolin En el campo del feminismo estructuralista Patricia
2018-11-13
En el campo del feminismo estructuralista, Patricia Hill Collins (2000) fue la primera en hablar de la interseccionalidad como un paradigma; sin embargo, fue Ange Marie Hancock (2007) quien propuso una formalización de este paradigma, entendido como un conjunto que engloba Forskolin la vez teoría no
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