• Pilsicainide might increase hERG proteins via facilitating t

  2019-06-29

  

  Pilsicainide might increase hERG proteins via facilitating the transcription of hERG from DNA to RNA or the translation of hERG RNA into hERG protein. Qualitative RT-PCR demonstrated the absence of an increase in hERG mRNA expression levels after pilsicainide treatment (Supplemental Fig. S2), indica

• Recent studies have analyzed the miRNA

  2019-06-29

  

  Recent studies have analyzed the miRNA profile of serum and bile samples from patients with PSC and patients with CCA complicating PSC. Overall, the miRNA expression of all analyzed miRNAs from both patients with PSC and patients with CCA complicating PSC was significantly higher compared with healt

• To assess quality independent from

  2019-06-29

  

  To assess quality independent from quantity, Imamura and colleagues assessed dietary intake adjusted for 2000 kcal per day. An unfortunate consequence of this adjustment is that the role of unrestrained energy intake in the obesity and diabetes epidemics seems to be rendered obsolete. For example, i

• CaMKII phosphorylation of L type

  2019-06-29

  

  CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 NHS-SS-Biotin molecular and predisposing to early afterdepolarizations. Recently iden

• Introduction Atrial fibrillation AF is a

  2019-06-29

  

  Introduction Atrial fibrillation (AF) is a highly prevalent atrial arrhythmia that affects approximately 10% of individuals older than 75 years of age and tends to increase in prevalence with advancing age [1–3]. Although AF itself is not life threatening, it is a risk factor for stroke, and the AF

• La ignorancia que evidencia Xa Am rica

  2019-06-28

  

  La ignorancia que evidencia Xa. América poética respecto de los literatos mexicanos corrobora la falta de proximidad entre zonas tan distantes del orbe hispanoamericano. Al mismo tiempo comprueba el vacío biográfico que en este punto muestran las revistas mexicanas o, más exactamente, El Recreo de l

• Confluye aqu en su literalidad en su capacidad

  2019-06-28

  

  Confluye aquí, en su literalidad, en su capacidad para evocar cierta “representación pura y simple de lo real”, esa retórica del cuerpo Pyrene azide 3 la que hice referencia más arriba. “Cuerpo-texto que destruye el cuerpo-carne pero se monta en él para transformarlo, para sustituirlo”, en la Histor

• Sin embargo las identidades sexuales politizadas no han

  2019-06-28

  

  Sin embargo, las identidades sexuales politizadas no han sido simples corolarios de la homofobia y trato despectivo hacia las sexualidades contra culturales. Para hacerse visibles, requirieron complejas condiciones sociales y políticas con el fin de producir un sentido de experiencia de comunidad qu

• br Results Karyotyping revealed chromosomal abnormalities in

  2019-06-28

  

  Results Karyotyping revealed chromosomal abnormalities in 19 of 20 metaphase spreads examined. All abnormal metaphases had a del(14)(q22), and 17 metaphases were interpreted to contain a three way translocation, t(2;5;7)(q31;q21;q11.2) and loss of all or part of chromosome 6. FISH analysis showed

• On what might an argument for a fairer distribution

  2019-06-28

  

  On what might an argument for a fairer distribution of malaria research investment rest? The investments analysed by Head and colleagues were those made from outside of sub-Saharan Africa, not by African countries themselves, and were a mix of public funds channelled through bilateral and multilater

• In contrast the prevalence of BS or Brugada type ECG

  2019-06-28

  

  In contrast, the prevalence of BS or Brugada-type ECG in Asian countries is relatively high. Type 1 ECG has been identified in 0.17% of 3907 asymptomatic Filipinos [24] and in 0.13% of 20,652 Taiwanese patients who visited the hospital for non-cardiovascular reasons [25]. Brugada-type ECG has been o

• br Discussion Treatment of patients

  2019-06-28

  

  Discussion Treatment of patients with vaginal leiomyosarcoma is challenging because of the rarity of this disease and a lack of controlled clinical trials comparing management strategies. At this time primary surgery remains the mainstay of management of vaginal leiomyosarcoma. Treatment plans sh

• De ser posible esta marcaci n temporal no se

  2019-06-28

  

  De ser posible esta marcación temporal, ¿no se correría el riesgo de fragmentar el pensamiento del autor? Por el contrario, si se contemplara todo el contenido de las obras de Morin con sus ideas de la complejidad, ¿no se asumiría el riesgo de globalizar y forzar su pensamiento? El propio Morin se h

• br Conflict of interest br Acknowledgments The project has

  2019-06-28

  

  Conflict of interest Acknowledgments The project has been supported by grants from Science Foundation Ireland, Ireland (Starting Investigator Research Grant to ES, 09/SIRG/B1575, TIDA to ES 12/TIDA/B2388) and by the Millennium Fund of NUIG. The t(3;21)(q26;q22) is a rare cytogenetic abnorma

• The prevalence of drug induced type Brugada pattern

  2019-06-28

  

  The prevalence of drug-induced type 1 Brugada pattern among patients with clinical AVNRT was found to be 27.1% by our group [17]. This high prevalence has important implications in terms of the epidemiology of BrS. The prevalence of paroxysmal supraventricular tachycardia (PSVT) (AVNRT and AVRT) in

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