The exogenous addition of osteogenically derived EVs outperf

2018-10-20

The exogenous addition of osteogenically derived EVs outperformed the effect of current osteoinductive strategies in terms of the type and/or intensity of the signaling, with the early activation of the key osteogenic commitment genes SP7 (Figure 3B) and BMP2 (Figure 3C), considered necessary and su

br Results br Discussion The primary cilium is a microtubule

2018-10-20

Results Discussion The primary cilium is a microtubule-containing cellular protrusion, which is anchored to a Ponatinib constituted of a mother centriole acting as a microtubule organizing center during ciliogenesis (Kim and Dynlacht, 2013). Thus, it is widely accepted that primary cilia must

br Experimental Procedures br Author Contributions br Acknow

2018-10-20

Experimental Procedures Author Contributions Acknowledgments The authors would like to thank the many people who contributed to this FLAG tag Peptide project, with numerous feedback and involvement. We thank the Australian Genome Research Facility for running microarray samples; thanks also

Patients with recessively inherited PARK Parkin Kitada

2018-10-20

Patients with recessively inherited PARK2/Parkin (Kitada et al., 1998) and PTEN-induced putative kinase 1 (PINK1) (Valente et al., 2004) mutations represent one of several monogenic forms of PD. Recent studies demonstrated the involvement of both Parkin and PINK1 in mitochondrial function (Imaizumi

As a marker of cochlear supporting cells we assessed P

2018-10-20

As a marker of cochlear supporting cells, we assessed P27Kip1 localization in iCx26GJCs. P27Kip1 is a cyclin-dependent kinase inhibitor that is thought to play a role in maintaining the postmitotic state of cochlear supporting cysteine protease such as the Deiters\' cells and outer- and inner-sulcus

Hello world!

2018-07-29